node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_3904 | dapA | PC1_3904 | PC1_1139 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.555 |
PC1_3904 | dapB | PC1_3904 | PC1_3649 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.482 |
PC1_3904 | dapF | PC1_3904 | PC1_3975 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.938 |
PC1_3904 | lysA | PC1_3904 | PC1_3486 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.937 |
PC1_3904 | murE | PC1_3904 | PC1_3597 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.916 |
PC1_3972 | PC1_3974 | PC1_3972 | PC1_3974 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4180 flavin mononucleotide phosphatase. | PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein. | 0.822 |
PC1_3972 | dapF | PC1_3972 | PC1_3975 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4180 flavin mononucleotide phosphatase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.800 |
PC1_3972 | xerC | PC1_3972 | PC1_3973 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4180 flavin mononucleotide phosphatase. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...] | 0.824 |
PC1_3974 | PC1_3972 | PC1_3974 | PC1_3972 | PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA4180 flavin mononucleotide phosphatase. | 0.822 |
PC1_3974 | dapF | PC1_3974 | PC1_3975 | PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.926 |
PC1_3974 | xerC | PC1_3974 | PC1_3973 | PFAM: protein of unknown function DUF484; KEGG: eca:ECA4182 hypothetical protein. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...] | 0.878 |
carB | dapF | PC1_3647 | PC1_3975 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; protein of unknown function DUF201; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: eca:ECA3870 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.836 |
dapA | PC1_3904 | PC1_1139 | PC1_3904 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | 0.555 |
dapA | dapB | PC1_1139 | PC1_3649 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.995 |
dapA | dapF | PC1_1139 | PC1_3975 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.796 |
dapA | lysA | PC1_1139 | PC1_3486 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.774 |
dapB | PC1_3904 | PC1_3649 | PC1_3904 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: eca:ECA4114 putative lysine/ornithine decarboxylase. | 0.482 |
dapB | dapA | PC1_3649 | PC1_1139 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.995 |
dapB | dapE | PC1_3649 | PC1_1169 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.456 |
dapB | dapF | PC1_3649 | PC1_3975 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.799 |