node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_2946 | PC1_3389 | PC1_2946 | PC1_3389 | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.911 |
PC1_2946 | PC1_4211 | PC1_2946 | PC1_4211 | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.911 |
PC1_2946 | gppA | PC1_2946 | PC1_4014 | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.911 |
PC1_2946 | polA | PC1_2946 | PC1_4227 | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.406 |
PC1_2946 | ppk | PC1_2946 | PC1_2945 | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.952 |
PC1_3205 | gppA | PC1_3205 | PC1_4014 | PFAM: cytochrome c assembly protein; KEGG: eca:ECA3361 hypothetical protein. | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.408 |
PC1_3389 | PC1_2946 | PC1_3389 | PC1_2946 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.911 |
PC1_3389 | PC1_4211 | PC1_3389 | PC1_4211 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.916 |
PC1_3389 | gppA | PC1_3389 | PC1_4014 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.923 |
PC1_3389 | polA | PC1_3389 | PC1_4227 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.524 |
PC1_4012 | gppA | PC1_4012 | PC1_4014 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: eca:ECA4212 thioredoxin; Belongs to the thioredoxin family. | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.572 |
PC1_4012 | rhlB | PC1_4012 | PC1_4013 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: eca:ECA4212 thioredoxin; Belongs to the thioredoxin family. | DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.549 |
PC1_4211 | PC1_2946 | PC1_4211 | PC1_2946 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.911 |
PC1_4211 | PC1_3389 | PC1_4211 | PC1_3389 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.916 |
PC1_4211 | gppA | PC1_4211 | PC1_4014 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.911 |
PC1_4211 | polA | PC1_4211 | PC1_4227 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.526 |
gppA | PC1_2946 | PC1_4014 | PC1_2946 | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.911 |
gppA | PC1_3205 | PC1_4014 | PC1_3205 | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | PFAM: cytochrome c assembly protein; KEGG: eca:ECA3361 hypothetical protein. | 0.408 |
gppA | PC1_3389 | PC1_4014 | PC1_3389 | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.923 |
gppA | PC1_4012 | PC1_4014 | PC1_4012 | Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: eca:ECA4212 thioredoxin; Belongs to the thioredoxin family. | 0.572 |