STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASHR1Histone-lysine N-methyltransferase ASHR1. (456 aa)    
Predicted Functional Partners:
DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.857
SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
     
 0.813
set1
Histone-lysine N-methyltransferase set1.
    
 0.811
SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific.
    
 0.811
clr4_1
Histone-lysine N-methyltransferase, H3 lysine-9 specific.
   
 
 0.800
set9
Histone-lysine N-methyltransferase set9.
     
 0.783
clr4_0
Histone-lysine N-methyltransferase, H3 lysine-9 specific.
     
 0.767
A0H81_11817
Uncharacterized protein.
     
 0.748
ash2
Set1 complex component ash2.
    
 0.725
Rbbp5
Retinoblastoma-binding protein 5.
    
 0.724
Your Current Organism:
Grifola frondosa
NCBI taxonomy Id: 5627
Other names: G. frondosa, maitake
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.