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dpaL protein (Brachyspira hyodysenteriae) - STRING interaction network
"dpaL" - Diaminopropionate ammonia-lyase in Brachyspira hyodysenteriae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpaLDiaminopropionate ammonia-lyase (397 aa)    
Predicted Functional Partners:
BHWA1_00067
Hypothetical protein (217 aa)
 
          0.961
argE
Peptidase (443 aa)
   
  0.939
BHWA1_00064
Ornithine carbamoyltransferase (379 aa)
 
   
  0.874
BHWA1_01047
Acetolactate synthase large subunit (557 aa)
   
  0.864
gltD
Oxidoreductase, Fe-S subunit (976 aa)
 
      0.863
BHWA1_01046
Acetolactate synthase small subunit (175 aa)
   
 
  0.855
ssnA
Chlorohydrolase/aminohydrolase (443 aa)
 
      0.832
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (187 aa)
   
      0.780
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (351 aa)
     
  0.765
BHWA1_02127
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (266 aa)
     
      0.751
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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