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groL protein (Brachyspira hyodysenteriae) - STRING interaction network
"groL" - Chaperonin GroEL in Brachyspira hyodysenteriae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (543 aa)    
Predicted Functional Partners:
groS
Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (88 aa)
 
 
  0.999
dnaK
Molecular chaperone DnaK; Acts as a chaperone (622 aa)
 
  0.995
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (200 aa)
 
  0.982
BHWA1_01681
Glyceraldehyde-3-phosphate dehydrogenase (347 aa)
   
  0.929
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa)
 
 
  0.910
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity (639 aa)
     
 
  0.879
pheT
phenylalanyl-tRNA synthetase alpha chain (807 aa)
   
 
  0.869
tuf
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (408 aa)
   
 
  0.852
thrS
threonyl-tRNA synthetase (643 aa)
   
 
  0.835
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1173 aa)
   
 
  0.816
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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