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STRINGSTRING
ACN83057.1 protein (Brachyspira hyodysenteriae) - STRING interaction network
"ACN83057.1" - annotation not available in Brachyspira hyodysenteriae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACN83057.1annotation not available (208 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (475 aa)
   
  0.927
sdaA
annotation not available (299 aa)
         
  0.907
sdaB
annotation not available (224 aa)
         
  0.907
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (417 aa)
   
 
  0.902
serA
annotation not available (534 aa)
   
 
  0.865
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (462 aa)
      0.838
ACN83014.1
annotation not available (242 aa)
         
  0.810
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (920 aa)
         
  0.534
ACN83059.1
annotation not available (381 aa)
   
 
  0.522
pheA
annotation not available (375 aa)
   
   
  0.433
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1
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