STRINGSTRING
BHWA1_00578 protein (Brachyspira hyodysenteriae) - STRING interaction network
"BHWA1_00578" - 3-deoxy-7-phosphoheptulonate synthase in Brachyspira hyodysenteriae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BHWA1_005783-deoxy-7-phosphoheptulonate synthase (347 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthetase (358 aa)
 
   
  0.991
pheA
Prephenate dehydratase (375 aa)
     
  0.939
tyrC
Prephenate dehydrogenase (286 aa)
 
 
  0.880
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (369 aa)
 
   
  0.871
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate (420 aa)
 
   
  0.863
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (175 aa)
       
    0.824
BHWA1_02403
3-deoxy-7-phosphoheptulonate synthase (343 aa)
   
   
 
0.801
patA
Aminotransferase A (377 aa)
       
    0.568
BHWA1_00947
Aspartate aminotransferase (398 aa)
       
    0.568
BHWA1_00946
Aspartate aminotransferase (399 aa)
       
    0.568
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
Server load: low (12%) [HD]