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def protein (Brachyspira hyodysenteriae) - STRING interaction network
"def" - N-formylmethionyl-tRNA deformylase in Brachyspira hyodysenteriae
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Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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defN-formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (187 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (293 aa)
 
  0.982
BHWA1_02089
ATPase with chaperone activity (518 aa)
          0.892
BHWA1_00848
HAD-super family hydrolase (220 aa)
   
        0.863
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (198 aa)
 
   
  0.848
rplQ
50S ribosomal protein L17 (128 aa)
     
 
  0.776
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (300 aa)
 
   
  0.773
rpe
Ribulose-phosphate 3-epimerase (233 aa)
 
 
  0.746
rplV
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) (135 aa)
     
      0.712
yhhF
N6-adenine-specific methylase (187 aa)
 
        0.647
folD
Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (281 aa)
         
  0.636
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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