STRINGSTRING
radC2 protein (Brachyspira hyodysenteriae) - STRING interaction network
"radC2" - DNA repair protein RadC in Brachyspira hyodysenteriae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radC2DNA repair protein RadC (233 aa)    
Predicted Functional Partners:
BHWA1_00857
Transcriptional regulator (139 aa)
              0.859
mutL
D mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (615 aa)
 
   
  0.841
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (887 aa)
 
     
  0.808
dprA
DNA protecting protein DprA (416 aa)
   
   
  0.771
pheT
phenylalanyl-tRNA synthetase alpha chain (807 aa)
 
 
 
  0.770
comF
Phosphoribosyltransferace (243 aa)
 
        0.658
polA
DNA polymerase I (920 aa)
     
 
  0.616
pyrFE
Orotidine 5’-phosphate decarboxylase/orotate phosphoribosyltransferase (451 aa)
 
          0.560
BHWA1_02089
ATPase with chaperone activity (518 aa)
 
   
  0.553
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (682 aa)
         
  0.546
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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