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BHWA1_00962 protein (Brachyspira hyodysenteriae) - STRING interaction network
"BHWA1_00962" - Hemolysin in Brachyspira hyodysenteriae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BHWA1_00962Hemolysin (432 aa)    
Predicted Functional Partners:
BHWA1_00464
5-methyltetrahydrofolate--homocysteine methyltransferase (873 aa)
       
    0.699
BHWA1_02644
3-oxoacyl-ACP (acyl carrier protein) reductase (249 aa)
     
 
    0.680
rpmA
50S ribosomal protein L27 (84 aa)
   
      0.652
lnt
Apolipoprotein N-acyltransferase; Transfers the fatty acyl group on membrane lipoproteins (768 aa)
         
  0.628
BHWA1_00960
Histidinol-phosphatase (281 aa)
              0.507
polA
DNA polymerase I (920 aa)
   
   
  0.504
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (394 aa)
         
  0.499
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa)
   
        0.497
dnaB
DNA helicase, DnaB type; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity (466 aa)
         
  0.496
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (217 aa)
         
  0.494
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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