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BHWA1_00989 protein (Brachyspira hyodysenteriae) - STRING interaction network
"BHWA1_00989" - LepB, Signal peptidase I in Brachyspira hyodysenteriae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BHWA1_00989LepB, Signal peptidase I (179 aa)    
Predicted Functional Partners:
BHWA1_00773
Signal peptidase I (243 aa)
   
   
 
0.849
BHWA1_02481
Leader peptidase (349 aa)
   
   
    0.825
BHWA1_00988
Nudix hydrolase (188 aa)
 
          0.760
BHWA1_00987
Hypothetical protein (317 aa)
              0.728
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (603 aa)
   
   
  0.576
pyrFE
Orotidine 5’-phosphate decarboxylase/orotate phosphoribosyltransferase (451 aa)
   
   
  0.568
soj
Sporulation initiation inhibitor protein Soj (254 aa)
 
          0.556
spo0J
Stage 0 sporulation protein J (320 aa)
 
          0.555
BHWA1_02052
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a "tag peptide", a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (161 aa)
 
          0.551
BHWA1_00045
Dihydroorotase (410 aa)
 
          0.548
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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