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ilvC protein (Brachyspira hyodysenteriae) - STRING interaction network
"ilvC" - Ketol-acid reductoisomerase in Brachyspira hyodysenteriae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvCKetol-acid reductoisomerase (331 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase (560 aa)
 
  0.999
BHWA1_01046
Acetolactate synthase small subunit (175 aa)
 
  0.999
BHWA1_01047
Acetolactate synthase large subunit (557 aa)
 
 
  0.999
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (278 aa)
         
  0.969
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (362 aa)
 
   
  0.828
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (206 aa)
     
   
  0.827
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (498 aa)
   
   
  0.825
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (415 aa)
   
   
  0.808
leuD
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (163 aa)
   
   
  0.791
purL
Phosphoribosylformylglycinamidine synthase (1248 aa)
     
   
  0.758
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae, B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1, Serpula hyodysenteriae, Serpulina hyodysenteriae, Treponema hyodysenteriae
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