STRINGSTRING
pyrD protein (Brachyspira hyodysenteriae) - STRING interaction network
"pyrD" - Dihydroorotate dehydrogenase B in Brachyspira hyodysenteriae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily (303 aa)    
Predicted Functional Partners:
pyrK
annotation not available (255 aa)
  0.998
pyrFE
Multifunctional fusion protein; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily (451 aa)
 
 
  0.996
ACN82548.1
annotation not available (410 aa)
 
  0.963
ACN83703.1
annotation not available (466 aa)
 
  0.898
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (514 aa)
 
   
  0.893
ACN84041.1
annotation not available (275 aa)
 
  0.889
purL
annotation not available (1248 aa)
   
   
  0.749
purD
annotation not available (417 aa)
 
 
  0.726
ACN83005.1
annotation not available (723 aa)
   
 
  0.722
pyrB
annotation not available (359 aa)
 
   
  0.714
Your Current Organism:
Brachyspira hyodysenteriae
NCBI taxonomy Id: 565034
Other names: B. hyodysenteriae WA1, Brachyspira hyodysenteriae, Brachyspira hyodysenteriae WA1, Brachyspira hyodysenteriae str. WA1, Brachyspira hyodysenteriae strain WA1
Server load: low (14%) [HD]