STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (440 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 0.998
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.995
pgk
Phosphoglycerate kinase; Identified by match to protein family HMM PF00162.
 
 
 0.992
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.990
fba
Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859.
  
 0.983
ACI60029.1
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
  
 0.981
rplD
Ribosomal protein L4/L1 family; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.973
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.938
tkt
Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; Belongs to the transketolase family.
  
 0.933
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.923
Your Current Organism:
Ureaplasma urealyticum
NCBI taxonomy Id: 565575
Other names: U. urealyticum serovar 10 str. ATCC 33699, Ureaplasma urealyticum serovar 10 str. ATCC 33699, Ureaplasma urealyticum serovar 10 strain ATCC 33699
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