STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_03_0590Putative DNA repair helicase. (1359 aa)    
Predicted Functional Partners:
LMJF_24_1680
VWFA domain-containing protein.
    
 0.898
LMJF_36_0800
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.892
LMJF_26_0040
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.888
LMJF_29_1790
BRCT domain-containing protein.
  
 0.884
LMJF_17_0540
AAA domain-containing protein.
   
 
 0.882
LMJF_32_1280
Putative RNA polymerase-like protein.
    
  0.819
LMJF_28_0810
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.819
LMJF_27_1550
DNA-directed RNA polymerase II-like protein.
    
  0.807
LMJF_26_1110
Uncharacterized protein.
   
 0.789
LMJF_19_1390
Transcription initiation factor-like protein (TFIID-like protein).
   
 0.771
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.