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JBP2 protein (Leishmania major) - STRING interaction network
"JBP2" - Bifunctional helicase and thymine dioxygenase JBP2 in Leishmania major
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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JBP2Bifunctional helicase and thymine dioxygenase JBP2; Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5- hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis. Involved in [...] (1022 aa)    
Predicted Functional Partners:
LmjF.28.0120
DNA-direcetd RNA polymerase II, subunit 9, putative.[Source-GeneDB;Acc-LmjF.28.0120] (140 aa)
       
 
  0.889
RPOIILS
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1662 aa)
       
 
  0.887
LmjF.35.3590
DNA repair protein RAD2, putative.[Source-GeneDB;Acc-LmjF.35.3590] (931 aa)
   
 
  0.775
LmjF.31.0160
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1185 aa)
     
 
  0.734
RBP38
Mitochondrial RNA binding protein, putative.[Source-GeneDB;Acc-LmjF.23.0760] (348 aa)
           
  0.725
LmjF.35.3450
DNA-repair protein, putative.[Source-GeneDB;Acc-LmjF.35.3450] (840 aa)
     
 
  0.678
LmjF.27.2300
Transcription elongation regulator-like protein.[Source-GeneDB;Acc-LmjF.27.2300] (700 aa)
   
 
  0.634
LmjF.08.0140
DNA repair protein, putative.[Source-GeneDB;Acc-LmjF.08.0140] (1260 aa)
   
 
  0.633
LmjF.24.2280
Putative DNA excision repair protein; TFIIH basal transcription factor complex helicase subunit, putative.[Source-GeneDB;Acc-LmjF.24.2280] (813 aa)
   
 
  0.625
LmjF.30.3300
UV excision repair RAD23-like protein.[Source-GeneDB;Acc-LmjF.30.3300] (425 aa)
       
 
  0.608
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania major, Leishmania tropica major
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