STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_32_2320Putative C-14 sterol reductase. (437 aa)    
Predicted Functional Partners:
LMJF_11_1100
Putative lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family.
   
 0.981
LMJF_06_0650
Putative lanosterol synthase; Belongs to the terpene cyclase/mutase family.
  
  
 0.939
LMJF_13_1620
Squalene monooxygenase-like protein.
  
 
 0.885
LMJF_30_3550
Cytochrome p450-like protein; Belongs to the cytochrome P450 family.
   
 
 0.875
LMJF_29_2140
C-8 sterol isomerase-like protein.
   
 
 0.843
LMJF_06_0350
NAD(P)-dependent steroid dehydrogenase-like protein; Belongs to the 3-beta-HSD family.
   
 
 0.843
LMJF_36_2540
Putative C-4 sterol methyl oxidase; Belongs to the sterol desaturase family.
   
 
 0.822
LMJF_23_1300
Lathosterol oxidase-like protein; Belongs to the sterol desaturase family.
   
 
 0.695
P883.21
Possible sterol desaturase-related protein; Belongs to the sterol desaturase family.
   
 
 0.695
LmSMT
Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
 
 
 
 0.652
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.