STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_28_2270Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (605 aa)    
Predicted Functional Partners:
LMJF_36_4590
Uncharacterized protein.
    
 0.850
LMJF_34_3500
RuvB-like helicase; Belongs to the RuvB family.
   
 0.787
ALP4
Putative actin-like protein; Belongs to the actin family.
   
 0.769
LMJF_02_0120
Putative phosphatidylinositol kinase related protein; Belongs to the PI3/PI4-kinase family.
    
 0.658
LMJF_29_1790
BRCT domain-containing protein.
    
 0.625
LMJF_24_1370
Putative histone deacetylase.
   
 0.597
LMJF_21_0680
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.597
LMJF_28_0530
RAD50 DNA repair-like protein.
   
 0.589
L7845.05
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.582
LMJF_15_0010
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.582
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.