LMJF_19_1190 protein (Leishmania major) - STRING interaction network

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LMJF_19_1190

CHCH domain-containing protein. (130 aa)

Predicted Functional Partners:

DHFR-TS

0.619

LMJF_16_1310

0.612

LMJF_22_1530

0.503

LMJF_25_1900

0.445

LMJF_35_3160

0.409

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR-TS	LMJF_16_1310	P07382	Q4QEN5	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.504
DHFR-TS	LMJF_19_1190	P07382	Q4QD96	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	CHCH domain-containing protein.	0.619
DHFR-TS	LMJF_22_1530	P07382	Q4QBJ4	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative dephospho-CoA kinase.	0.643
DHFR-TS	LMJF_25_1900	P07382	Q4Q9P9	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.569
DHFR-TS	LMJF_35_3160	P07382	E9AFE0	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Riboflavin kinase/fmn adenylyltransferase-like protein.	0.708
LMJF_16_1310	DHFR-TS	Q4QEN5	P07382	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.504
LMJF_16_1310	LMJF_19_1190	Q4QEN5	Q4QD96	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	CHCH domain-containing protein.	0.612
LMJF_16_1310	LMJF_25_1900	Q4QEN5	Q4Q9P9	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.583
LMJF_19_1190	DHFR-TS	Q4QD96	P07382	CHCH domain-containing protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.619
LMJF_19_1190	LMJF_16_1310	Q4QD96	Q4QEN5	CHCH domain-containing protein.	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.612
LMJF_19_1190	LMJF_22_1530	Q4QD96	Q4QBJ4	CHCH domain-containing protein.	Putative dephospho-CoA kinase.	0.503
LMJF_19_1190	LMJF_25_1900	Q4QD96	Q4Q9P9	CHCH domain-containing protein.	Uncharacterized protein.	0.445
LMJF_19_1190	LMJF_35_3160	Q4QD96	E9AFE0	CHCH domain-containing protein.	Riboflavin kinase/fmn adenylyltransferase-like protein.	0.409
LMJF_22_1530	DHFR-TS	Q4QBJ4	P07382	Putative dephospho-CoA kinase.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.643
LMJF_22_1530	LMJF_19_1190	Q4QBJ4	Q4QD96	Putative dephospho-CoA kinase.	CHCH domain-containing protein.	0.503
LMJF_22_1530	LMJF_25_1900	Q4QBJ4	Q4Q9P9	Putative dephospho-CoA kinase.	Uncharacterized protein.	0.576
LMJF_22_1530	LMJF_35_3160	Q4QBJ4	E9AFE0	Putative dephospho-CoA kinase.	Riboflavin kinase/fmn adenylyltransferase-like protein.	0.711
LMJF_25_1900	DHFR-TS	Q4Q9P9	P07382	Uncharacterized protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.569
LMJF_25_1900	LMJF_16_1310	Q4Q9P9	Q4QEN5	Uncharacterized protein.	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.583
LMJF_25_1900	LMJF_19_1190	Q4Q9P9	Q4QD96	Uncharacterized protein.	CHCH domain-containing protein.	0.445