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JBP2 protein (Leishmania infantum) - STRING interaction network
"JBP2" - Bifunctional helicase and thymine dioxygenase JBP2 in Leishmania infantum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JBP2Bifunctional helicase and thymine dioxygenase JBP2; Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5- hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis. Involved in [...] (1022 aa)    
Predicted Functional Partners:
XP_001470047.1
Putative DNA-direcetd RNA polymerase II, subunit 9 (140 aa)
       
 
  0.862
XP_001469167.1
Putative DNA repair protein RAD2 (930 aa)
   
 
  0.789
XP_001467277.1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1181 aa)
     
 
  0.720
XP_001469154.1
Putative DNA-repair protein (840 aa)
     
 
  0.691
XP_001468849.1
Uncharacterized protein (1233 aa)
       
 
  0.662
RPOIILS
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1662 aa)
       
 
  0.662
XP_001463356.1
Putative DNA repair protein (1260 aa)
   
 
  0.658
XP_001466027.1
TFIIH basal transcription factor complex helicase subunit; Putative DNA excision repair protein; putative putative RAD3/XPD protein (813 aa)
   
 
  0.647
RBP38
Putative mitochondrial RNA binding protein (348 aa)
           
  0.638
XP_001466459.1
Transcription elongation regulator-like protein (700 aa)
   
 
  0.630
Your Current Organism:
Leishmania infantum
NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum, Leishmania infantum
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