STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LINJ_28_1350Putative p450 reductase. (645 aa)    
Predicted Functional Partners:
LINJ_28_0410
Phosphoadenosine phosphosulfate reductase-like protein.
  
 
 0.812
LinJ07.0210
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
   
 0.742
CYSB
Cystathionine beta-synthase.
  
 
 0.727
LINJ_36_3750
Cysteine synthase.
  
 
 0.727
LINJ_30_0630
Putative nitrate reductase.
    
 0.654
LINJ_07_0240
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 0.610
LINJ_36_6570
Putative homocysteine S-methyltransferase.
  
 0.610
LINJ_31_1650
Uncharacterized protein.
   
 
 0.547
LINJ_23_0300
Putative argininosuccinate synthase.
     
 0.521
PEX14
Putative peroxin 14.
     
 0.512
Your Current Organism:
Leishmania infantum
NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.