STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLBEP00000013081Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)    
Predicted Functional Partners:
hat1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
    
 0.862
mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.861
ENSLBEP00000011618
Tudor domain-containing protein.
    
 0.820
arid4a
AT rich interactive domain 4A (RBP1-like).
    
 0.820
rbbp5
Retinoblastoma binding protein 5.
    
 0.811
ENSLBEP00000009844
Histone H2A; Belongs to the histone H2A family.
   
 0.809
LOC109991317
Histone H2A; Belongs to the histone H2A family.
   
 0.809
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.801
ENSLBEP00000002429
Lysine (K)-specific demethylase 6B, b.
    
 0.798
LOC109990604
Lysine (K)-specific demethylase 6B, a.
    
 0.798
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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