STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiOABC-type cobalt transport system, ATPase component; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (280 aa)    
Predicted Functional Partners:
SYN_00208
ABC-type cobalt transport system, permease component.
 0.999
SYN_00210
Hypothetical membrane protein.
 
 
 0.989
SYN_01995
Export ABC transporter permease protein.
 
 
    0.896
SYN_00854
Export ABC transporter permease protein.
 
 
    0.887
birA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.703
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
 
    0.656
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
     0.615
SYN_02172
Oligopeptide transport ATP-binding protein; Belongs to the ABC transporter superfamily.
 
 
0.600
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
  
 0.594
SYN_02272
uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional.
     
 0.546
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.