node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_00133 | SYN_00471 | SYN_00133 | SYN_00471 | Lipid A biosynthesis lauroyl acyltransferase. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.801 |
SYN_00133 | lpxA | SYN_00133 | SYN_01567 | Lipid A biosynthesis lauroyl acyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.828 |
SYN_00133 | lpxB | SYN_00133 | SYN_01565 | Lipid A biosynthesis lauroyl acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.843 |
SYN_00133 | lpxC | SYN_00133 | SYN_00756 | Lipid A biosynthesis lauroyl acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.832 |
SYN_00133 | lpxD | SYN_00133 | SYN_01568 | Lipid A biosynthesis lauroyl acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.844 |
SYN_00133 | lpxK | SYN_00133 | SYN_01563 | Lipid A biosynthesis lauroyl acyltransferase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.827 |
SYN_00133 | msbA | SYN_00133 | SYN_01564 | Lipid A biosynthesis lauroyl acyltransferase. | Phospholipid-lipopolysaccharide ABC transporter; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.481 |
SYN_00471 | SYN_00133 | SYN_00471 | SYN_00133 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid A biosynthesis lauroyl acyltransferase. | 0.801 |
SYN_00471 | lpxA | SYN_00471 | SYN_01567 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.871 |
SYN_00471 | lpxB | SYN_00471 | SYN_01565 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.878 |
SYN_00471 | lpxC | SYN_00471 | SYN_00756 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.873 |
SYN_00471 | lpxD | SYN_00471 | SYN_01568 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.880 |
SYN_00471 | lpxK | SYN_00471 | SYN_01563 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.902 |
SYN_00471 | msbA | SYN_00471 | SYN_01564 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Phospholipid-lipopolysaccharide ABC transporter; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.602 |
SYN_01366 | lpxA | SYN_01366 | SYN_01567 | Calcineurin-like phosphoesterase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.420 |
SYN_01366 | lpxB | SYN_01366 | SYN_01565 | Calcineurin-like phosphoesterase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.951 |
SYN_01366 | lpxC | SYN_01366 | SYN_00756 | Calcineurin-like phosphoesterase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.483 |
SYN_01366 | lpxD | SYN_01366 | SYN_01568 | Calcineurin-like phosphoesterase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.943 |
SYN_01566 | lpxA | SYN_01566 | SYN_01567 | NAD-dependent oxidoreductase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.785 |
SYN_01566 | lpxB | SYN_01566 | SYN_01565 | NAD-dependent oxidoreductase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.949 |