node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_01778 | dut | SYN_01778 | SYN_01779 | Hypothetical cytosolic protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.773 |
SYN_01778 | pnp | SYN_01778 | SYN_01780 | Hypothetical cytosolic protein. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.773 |
SYN_01979 | SYN_03522 | SYN_01979 | SYN_03522 | Anaerobic ribonucleoside-triphosphate reductase. | Anaerobic ribonucleoside-triphosphate reductase. | 0.928 |
SYN_01979 | dut | SYN_01979 | SYN_01779 | Anaerobic ribonucleoside-triphosphate reductase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.917 |
SYN_02050 | dut | SYN_02050 | SYN_01779 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.922 |
SYN_02177 | dut | SYN_02177 | SYN_01779 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.974 |
SYN_02264 | SYN_02368 | SYN_02264 | SYN_02368 | UDP-sugar diphosphatase / 5'-nucleotidase; Bifunctional; Belongs to the 5'-nucleotidase family. | Deoxycytidylate deaminase. | 0.906 |
SYN_02264 | dut | SYN_02264 | SYN_01779 | UDP-sugar diphosphatase / 5'-nucleotidase; Bifunctional; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
SYN_02264 | surE | SYN_02264 | SYN_01984 | UDP-sugar diphosphatase / 5'-nucleotidase; Bifunctional; Belongs to the 5'-nucleotidase family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
SYN_02264 | tmk | SYN_02264 | SYN_03606 | UDP-sugar diphosphatase / 5'-nucleotidase; Bifunctional; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.911 |
SYN_02368 | SYN_02264 | SYN_02368 | SYN_02264 | Deoxycytidylate deaminase. | UDP-sugar diphosphatase / 5'-nucleotidase; Bifunctional; Belongs to the 5'-nucleotidase family. | 0.906 |
SYN_02368 | dut | SYN_02368 | SYN_01779 | Deoxycytidylate deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.941 |
SYN_02368 | surE | SYN_02368 | SYN_01984 | Deoxycytidylate deaminase. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
SYN_02368 | tmk | SYN_02368 | SYN_03606 | Deoxycytidylate deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.919 |
SYN_03522 | SYN_01979 | SYN_03522 | SYN_01979 | Anaerobic ribonucleoside-triphosphate reductase. | Anaerobic ribonucleoside-triphosphate reductase. | 0.928 |
SYN_03522 | dut | SYN_03522 | SYN_01779 | Anaerobic ribonucleoside-triphosphate reductase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.917 |
dut | SYN_01778 | SYN_01779 | SYN_01778 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Hypothetical cytosolic protein. | 0.773 |
dut | SYN_01979 | SYN_01779 | SYN_01979 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Anaerobic ribonucleoside-triphosphate reductase. | 0.917 |
dut | SYN_02050 | SYN_01779 | SYN_02050 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.922 |
dut | SYN_02177 | SYN_01779 | SYN_02177 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.974 |