node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_00110 | SYN_02378 | SYN_00110 | SYN_02378 | Chaperone protein dnaJ. | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | 0.632 |
SYN_00110 | clpB | SYN_00110 | SYN_02525 | Chaperone protein dnaJ. | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.632 |
SYN_00110 | dnaK | SYN_00110 | SYN_01983 | Chaperone protein dnaJ. | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.989 |
SYN_00110 | grpE | SYN_00110 | SYN_01981 | Chaperone protein dnaJ. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.905 |
SYN_00725 | SYN_02378 | SYN_00725 | SYN_02378 | Chaperone protein. | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | 0.658 |
SYN_00725 | clpB | SYN_00725 | SYN_02525 | Chaperone protein. | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.658 |
SYN_00725 | dnaK | SYN_00725 | SYN_01983 | Chaperone protein. | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.971 |
SYN_00725 | grpE | SYN_00725 | SYN_01981 | Chaperone protein. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.824 |
SYN_00894 | SYN_02378 | SYN_00894 | SYN_02378 | Chaperone protein. | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | 0.658 |
SYN_00894 | clpB | SYN_00894 | SYN_02525 | Chaperone protein. | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.658 |
SYN_00894 | dnaK | SYN_00894 | SYN_01983 | Chaperone protein. | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
SYN_00894 | grpE | SYN_00894 | SYN_01981 | Chaperone protein. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.941 |
SYN_02125 | dnaK | SYN_02125 | SYN_01983 | iscU protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.924 |
SYN_02125 | grpE | SYN_02125 | SYN_01981 | iscU protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.510 |
SYN_02378 | SYN_00110 | SYN_02378 | SYN_00110 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ. | 0.632 |
SYN_02378 | SYN_00725 | SYN_02378 | SYN_00725 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein. | 0.658 |
SYN_02378 | SYN_00894 | SYN_02378 | SYN_00894 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein. | 0.658 |
SYN_02378 | dnaJ | SYN_02378 | SYN_00026 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.646 |
SYN_02378 | dnaJ-2 | SYN_02378 | SYN_01906 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.646 |
SYN_02378 | dnaJ-3 | SYN_02378 | SYN_02711 | ATPase clp protease ATP binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] | 0.646 |