node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acin_0025 | aroA | Acin_0025 | Acin_0024 | Prephenate dehydrogenase tyrA. | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | 0.833 |
Acin_0025 | aroA-2 | Acin_0025 | Acin_0027 | Prephenate dehydrogenase tyrA. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.993 |
Acin_0025 | aroB | Acin_0025 | Acin_0026 | Prephenate dehydrogenase tyrA. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.943 |
Acin_0025 | aroC | Acin_0025 | Acin_0028 | Prephenate dehydrogenase tyrA. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.948 |
Acin_0025 | aroE | Acin_0025 | Acin_0030 | Prephenate dehydrogenase tyrA. | Shikimate dehydrogenase; COG1605. | 0.809 |
Acin_0025 | aroK | Acin_0025 | Acin_0031 | Prephenate dehydrogenase tyrA. | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.836 |
Acin_0025 | aroK-2 | Acin_0025 | Acin_0050 | Prephenate dehydrogenase tyrA. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.551 |
Acin_0025 | cmk | Acin_0025 | Acin_1170 | Prephenate dehydrogenase tyrA. | Cytidylate kinase; COG0283. | 0.717 |
Acin_0025 | pheA | Acin_0025 | Acin_0029 | Prephenate dehydrogenase tyrA. | Chorismate mutase; COG0077. | 0.987 |
aroA | Acin_0025 | Acin_0024 | Acin_0025 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Prephenate dehydrogenase tyrA. | 0.833 |
aroA | aroA-2 | Acin_0024 | Acin_0027 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.864 |
aroA | aroB | Acin_0024 | Acin_0026 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.995 |
aroA | aroC | Acin_0024 | Acin_0028 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.806 |
aroA | aroE | Acin_0024 | Acin_0030 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Shikimate dehydrogenase; COG1605. | 0.827 |
aroA | aroE-2 | Acin_0024 | Acin_0035 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.541 |
aroA | aroK | Acin_0024 | Acin_0031 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.742 |
aroA | aroK-2 | Acin_0024 | Acin_0050 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.458 |
aroA | pheA | Acin_0024 | Acin_0029 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | Chorismate mutase; COG0077. | 0.968 |
aroA-2 | Acin_0025 | Acin_0027 | Acin_0025 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydrogenase tyrA. | 0.993 |
aroA-2 | aroA | Acin_0027 | Acin_0024 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876. | 0.864 |