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ilvH protein (Acidaminococcus intestini) - STRING interaction network
"ilvH" - Acetolactate synthase 3 regulatory subunit in Acidaminococcus intestini
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ilvHAcetolactate synthase 3 regulatory subunit; COG0440 (166 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (337 aa)
 
  0.998
Acin_0109
Acetolactate synthase; COG0028 (572 aa)
  0.996
Acin_0041
Acetolactate synthase large subunit; COG0028; Belongs to the TPP enzyme family (611 aa)
  0.949
ilvA
Threonine dehydratase; COG1171 (404 aa)
   
 
  0.945
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (356 aa)
 
 
  0.941
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily (580 aa)
 
 
  0.936
ttuC
Tartrate dehydrogenase; COG0473 (359 aa)
 
 
  0.935
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (1143 aa)
     
 
  0.825
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (807 aa)
     
 
  0.821
pyk
Pyruvate kinase; COG3848; Belongs to the pyruvate kinase family (611 aa)
     
    0.819
Your Current Organism:
Acidaminococcus intestini
NCBI taxonomy Id: 568816
Other names: A. intestini RyC-MR95, Acidaminococcus intestini, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95
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