STRINGSTRING
holA protein (Acidaminococcus intestini) - STRING interaction network
"holA" - DNA polymerase III subunit delta in Acidaminococcus intestini
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holADNA polymerase III subunit delta (361 aa)    
Predicted Functional Partners:
holB
DNA polymerase III delta’ subunit (326 aa)
   
  0.997
dnaX
DNA polymerase III (610 aa)
     
  0.997
dnaN
DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (372 aa)
 
  0.995
dnaE
DNA polymerase III (1156 aa)
     
  0.992
pyk
Pyruvate kinase (611 aa)
       
    0.902
polA
DNA polymerase I (873 aa)
     
 
  0.900
nrdD
Ribonucleoside-triphosphate reductase (690 aa)
         
    0.900
Acin_0528
Hypothetical protein (766 aa)
 
        0.887
Acin_0527
Late competence protein comEA (210 aa)
              0.852
polC
DNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (1210 aa)
       
  0.802
Your Current Organism:
Acidaminococcus intestini
NCBI taxonomy Id: 568816
Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus intestini, Acidaminococcus intestini Jumas-Bilak et al. 2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99
Server load: low (11%) [HD]