STRINGSTRING
nth protein (Acidaminococcus intestini) - STRING interaction network
"nth" - Endonuclease III in Acidaminococcus intestini
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (210 aa)    
Predicted Functional Partners:
xthA
Exodeoxyribonuclease III (258 aa)
 
 
  0.997
Acin_0707
Hypothetical protein (453 aa)
              0.869
Acin_0706
Hypothetical protein (89 aa)
              0.819
nfo
Apurinic endonuclease apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5’-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (307 aa)
   
 
  0.819
polA
DNA polymerase I (873 aa)
   
 
  0.806
Acin_0709
Hypothetical protein (509 aa)
              0.775
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis (448 aa)
   
   
  0.732
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (427 aa)
         
  0.727
Acin_0710
Hypothetical protein (122 aa)
              0.680
gmhB
Histidinol-phosphate phosphatase (183 aa)
       
 
  0.657
Your Current Organism:
Acidaminococcus intestini
NCBI taxonomy Id: 568816
Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus intestini, Acidaminococcus intestini Jumas-Bilak et al. 2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99
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