STRINGSTRING
polC protein (Acidaminococcus intestini) - STRING interaction network
"polC" - DNA polymerase III in Acidaminococcus intestini
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (1210 aa)    
Predicted Functional Partners:
polA
DNA polymerase I (873 aa)
     
  0.956
dnaQ
DNA polymerase III (212 aa)
 
          0.935
pyk
Pyruvate kinase (611 aa)
         
  0.908
nrdD
Ribonucleoside-triphosphate reductase (690 aa)
         
    0.900
Acin_1604
MgtC/SapB transporter (222 aa)
              0.882
dnaN
DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (372 aa)
     
  0.850
dnaX
DNA polymerase III (610 aa)
     
  0.849
Acin_2291
Hypothetical protein (225 aa)
 
          0.848
dnaE
DNA polymerase III (1156 aa)
         
0.839
holB
DNA polymerase III delta’ subunit (326 aa)
   
 
  0.809
Your Current Organism:
Acidaminococcus intestini
NCBI taxonomy Id: 568816
Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus intestini, Acidaminococcus intestini Jumas-Bilak et al. 2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99
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