STRINGSTRING
trpC protein (Acidaminococcus intestini) - STRING interaction network
"trpC" - Indole-3-glycerol phosphate synthase in Acidaminococcus intestini
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCIndole-3-glycerol phosphate synthase (261 aa)    
Predicted Functional Partners:
trpF
Anthranilate synthase component II (210 aa)
  0.999
trpB
Tryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (394 aa)
 
  0.999
trpA
Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (257 aa)
 
  0.999
trpG
Anthranilate synthase component II (194 aa)
   
  0.997
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (340 aa)
   
  0.996
trpE
Anthranilate synthase component I (534 aa)
 
  0.996
hisI
phosphoribosyl-AMP cyclohydrolase (222 aa)
   
   
  0.846
pgk
Phosphoglycerate kinase (641 aa)
   
   
  0.764
hisF
Imidazoleglycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
   
   
  0.705
purL
Phosphoribosylformylglycinamidine synthase (1254 aa)
   
   
  0.703
Your Current Organism:
Acidaminococcus intestini
NCBI taxonomy Id: 568816
Other names: A. intestini, A. intestini RyC-MR95, Acidaminococcus intestini, Acidaminococcus intestini Jumas-Bilak et al. 2007, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95, Acidaminococcus sp. ADV 255.99
Server load: low (3%) [HD]