STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyr4Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. (314 aa)    
Predicted Functional Partners:
Q4DBC5_TRYCC
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative.
  
 0.993
Q4DBZ4_TRYCC
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative.
  
 0.993
Q4CRZ4_TRYCC
Dihydroorotase, putative.
  
 0.991
Q4CSV8_TRYCC
Dihydroorotase, putative.
  
 0.991
Q4DBC4_TRYCC
Dihydroorotase, putative.
  
 0.991
Q4CSV7_TRYCC
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative.
  
 0.943
Q4DHS6_TRYCC
Uncharacterized protein.
  
 
 0.930
Q4DPE0_TRYCC
Uncharacterized protein.
  
 
 0.930
Q4D6X8_TRYCC
Glutamine-dependent carbamoyl-phosphate synthetase, putative.
  
 0.915
Q4DBC3_TRYCC
Glutamine-dependent carbamoyl-phosphate synthetase, putative.
  
 0.915
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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