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TRS protein (Trypanosoma cruzi) - STRING interaction network
"TRS" - Trypanothione synthetase in Trypanosoma cruzi
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TRSTrypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family (647 aa)    
Predicted Functional Partners:
XP_811272.1
Spermidine synthase, putative; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053504033.130; Belongs to the spermidine/spermine synthase family (296 aa)
         
  0.975
XP_816871.1
Spermidine synthase, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053510339.50; Belongs to the spermidine/spermine synthase family (296 aa)
         
  0.975
XP_811725.1
Spermidine synthase, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053510337.40; Belongs to the spermidine/spermine synthase family (296 aa)
         
  0.975
XP_806851.1
Spermidine synthase, putative; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053503855.20; Belongs to the spermidine/spermine synthase family (296 aa)
         
  0.975
XP_805296.1
Trypanothione reductase, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053484299.10; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (492 aa)
       
  0.973
XP_814034.1
Glutathione peroxidase; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053511543.60; Belongs to the glutathione peroxidase family (160 aa)
       
  0.966
XP_807101.1
Glutathione peroxidase; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053511019.99; Belongs to the glutathione peroxidase family (225 aa)
       
  0.966
XP_820846.1
Glutathionylspermidine synthase, putative; Haploid, Esmeraldo-like haplotype (719 aa)
   
   
0.925
XP_810415.1
Glutathione synthetase; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053506659.30 (535 aa)
         
  0.919
XP_809479.1
Glutathione synthetase; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053508865.10 (535 aa)
         
  0.919
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 5693
Other names: T. cruzi, Trypanosoma cruzi
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