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JBP1B protein (Trypanosoma cruzi) - STRING interaction network
"JBP1B" - Thymine dioxygenase JBP1-B in Trypanosoma cruzi
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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JBP1BThymine dioxygenase JBP1-B; Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5- hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Also specifically binds to base J-containing DNA (J- DNA). Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized D [...] (831 aa)    
Predicted Functional Partners:
XP_815757.1
Helicase-like protein, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053508645.10 (1053 aa)
           
  0.624
XP_807662.1
Helicase-like protein, putative; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053506203.30 (1060 aa)
           
  0.624
XP_815423.1
DNA excision/repair protein SNF2, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053504797.70 (773 aa)
           
  0.442
XP_814373.1
DNA excision/repair protein SNF2, putative; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053511577.60 (729 aa)
           
  0.442
XP_807766.1
DNA excision repair protein, putative; Heterozygous, Esmeraldo-like haplotype; allele of Tc00.1047053506983.60 (1118 aa)
           
  0.442
XP_807298.1
DNA excision repair protein, putative; Heterozygous, non-Esmeraldo-like haplotype; allele of Tc00.1047053508675.20 (1114 aa)
           
  0.442
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 5693
Other names: T. cruzi, Trypanosoma cruzi
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