STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (485 aa)    
Predicted Functional Partners:
Q4E2M9_TRYCC
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.998
Q4E5N1_TRYCC
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.998
Q4D0Q0_TRYCC
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.990
Q4D4R9_TRYCC
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.990
Q4D4S0_TRYCC
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.990
Q4DV43_TRYCC
Triosephosphate isomerase.
  
 
 0.990
Q4CMZ5_TRYCC
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.985
Q4CUD7_TRYCC
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.985
Q4DU82_TRYCC
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.985
Q4D3P5_TRYCC
Phosphotransferase.
   
 
 0.984
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.