node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEO04162.1 | SEO04190.1 | SAMN04490248_101131 | SAMN04490248_101132 | Uncharacterized conserved protein, DUF2147 family. | Uncharacterized conserved protein, DUF2147 family. | 0.528 |
SEO04190.1 | SEO04162.1 | SAMN04490248_101132 | SAMN04490248_101131 | Uncharacterized conserved protein, DUF2147 family. | Uncharacterized conserved protein, DUF2147 family. | 0.528 |
SEO04190.1 | SEO92559.1 | SAMN04490248_101132 | SAMN04490248_11648 | Uncharacterized conserved protein, DUF2147 family. | Histidinol-phosphate aminotransferase. | 0.557 |
SEO04190.1 | SEP04484.1 | SAMN04490248_101132 | SAMN04490248_12118 | Uncharacterized conserved protein, DUF2147 family. | Threonine/homoserine efflux transporter RhtA. | 0.429 |
SEO04190.1 | hisA | SAMN04490248_101132 | SAMN04490248_101133 | Uncharacterized conserved protein, DUF2147 family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.564 |
SEO04190.1 | hisC | SAMN04490248_101132 | SAMN04490248_11249 | Uncharacterized conserved protein, DUF2147 family. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.499 |
SEO04190.1 | hisE | SAMN04490248_101132 | SAMN04490248_101135 | Uncharacterized conserved protein, DUF2147 family. | phosphoribosyl-ATP pyrophosphatase. | 0.430 |
SEO04190.1 | hisF | SAMN04490248_101132 | SAMN04490248_101134 | Uncharacterized conserved protein, DUF2147 family. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.705 |
SEO04190.1 | hisH | SAMN04490248_101132 | SAMN04490248_116101 | Uncharacterized conserved protein, DUF2147 family. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.499 |
SEO92559.1 | SEO04190.1 | SAMN04490248_11648 | SAMN04490248_101132 | Histidinol-phosphate aminotransferase. | Uncharacterized conserved protein, DUF2147 family. | 0.557 |
SEO92559.1 | hisA | SAMN04490248_11648 | SAMN04490248_101133 | Histidinol-phosphate aminotransferase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.792 |
SEO92559.1 | hisE | SAMN04490248_11648 | SAMN04490248_101135 | Histidinol-phosphate aminotransferase. | phosphoribosyl-ATP pyrophosphatase. | 0.817 |
SEO92559.1 | hisF | SAMN04490248_11648 | SAMN04490248_101134 | Histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.934 |
SEO92559.1 | hisH | SAMN04490248_11648 | SAMN04490248_116101 | Histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.954 |
SEP04484.1 | SEO04190.1 | SAMN04490248_12118 | SAMN04490248_101132 | Threonine/homoserine efflux transporter RhtA. | Uncharacterized conserved protein, DUF2147 family. | 0.429 |
hisA | SEO04190.1 | SAMN04490248_101133 | SAMN04490248_101132 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Uncharacterized conserved protein, DUF2147 family. | 0.564 |
hisA | SEO92559.1 | SAMN04490248_101133 | SAMN04490248_11648 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Histidinol-phosphate aminotransferase. | 0.792 |
hisA | hisC | SAMN04490248_101133 | SAMN04490248_11249 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.812 |
hisA | hisE | SAMN04490248_101133 | SAMN04490248_101135 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | phosphoribosyl-ATP pyrophosphatase. | 0.988 |
hisA | hisF | SAMN04490248_101133 | SAMN04490248_101134 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.992 |