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purA protein (Hamiltonella defensa) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Hamiltonella defensa
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (436 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (458 aa)
 
 
  0.990
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (480 aa)
 
 
  0.986
purH
Bifunctional purine biosynthesis protein PurH; COG0138 (533 aa)
 
  0.980
pyrB
Aspartate carbamoyltransferase; COG0540; Belongs to the ATCase/OTCase family (306 aa)
   
 
  0.945
thrA
Bifunctional- aspartokinase I (N-terminal); COG0460,COG0527 (820 aa)
   
 
  0.930
aspC_1
Aspartate aminotransferase, PLP-dependent-1; COG1448 (396 aa)
   
 
  0.912
asnB
Asparagine synthetase B; COG0367 (554 aa)
   
 
    0.908
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
 
   
  0.908
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate (536 aa)
         
  0.907
aspA
Aspartate ammonia-lyase; COG1027 (476 aa)
         
  0.904
Your Current Organism:
Hamiltonella defensa
NCBI taxonomy Id: 572265
Other names: C. Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa str. 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa strain 5AT (Acyrthosiphon pisum), Hamiltonella defensa
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