node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | asnS | HDEF_0639 | HDEF_0877 | Arginine tRNA synthetase; COG0018. | Asparagine tRNA synthetase; COG0017. | 0.801 |
argS | gltX | HDEF_0639 | HDEF_0366 | Arginine tRNA synthetase; COG0018. | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.817 |
argS | ileS | HDEF_0639 | HDEF_0831 | Arginine tRNA synthetase; COG0018. | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.917 |
argS | leuS | HDEF_0639 | HDEF_2038 | Arginine tRNA synthetase; COG0018. | Leucine tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.876 |
argS | lysU | HDEF_0639 | HDEF_0009 | Arginine tRNA synthetase; COG0018. | Lysine tRNA synthetase, inducible; COG1190; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.837 |
argS | metG | HDEF_0639 | HDEF_1807 | Arginine tRNA synthetase; COG0018. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.877 |
argS | pheT | HDEF_0639 | HDEF_1830 | Arginine tRNA synthetase; COG0018. | Phenylalanine tRNA synthetase, beta-subunit; COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.870 |
argS | proS | HDEF_0639 | HDEF_0391 | Arginine tRNA synthetase; COG0018. | Proline tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...] | 0.906 |
argS | thrS | HDEF_0639 | HDEF_1824 | Arginine tRNA synthetase; COG0018. | Threonine tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.656 |
asnS | argS | HDEF_0877 | HDEF_0639 | Asparagine tRNA synthetase; COG0017. | Arginine tRNA synthetase; COG0018. | 0.801 |
asnS | gltX | HDEF_0877 | HDEF_0366 | Asparagine tRNA synthetase; COG0017. | Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.791 |
asnS | ileS | HDEF_0877 | HDEF_0831 | Asparagine tRNA synthetase; COG0017. | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.875 |
asnS | leuS | HDEF_0877 | HDEF_2038 | Asparagine tRNA synthetase; COG0017. | Leucine tRNA synthetase; COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.860 |
asnS | lysU | HDEF_0877 | HDEF_0009 | Asparagine tRNA synthetase; COG0017. | Lysine tRNA synthetase, inducible; COG1190; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.669 |
asnS | metG | HDEF_0877 | HDEF_1807 | Asparagine tRNA synthetase; COG0017. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.850 |
asnS | pheT | HDEF_0877 | HDEF_1830 | Asparagine tRNA synthetase; COG0017. | Phenylalanine tRNA synthetase, beta-subunit; COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.805 |
asnS | proS | HDEF_0877 | HDEF_0391 | Asparagine tRNA synthetase; COG0017. | Proline tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...] | 0.857 |
asnS | thrS | HDEF_0877 | HDEF_1824 | Asparagine tRNA synthetase; COG0017. | Threonine tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.489 |
fmt | metG | HDEF_1721 | HDEF_1807 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.928 |
fmt | pheT | HDEF_1721 | HDEF_1830 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Phenylalanine tRNA synthetase, beta-subunit; COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.624 |