node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HDEF_0787 | purC | HDEF_0787 | HDEF_1837 | Colicin V production protein; COG1286. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); COG0152; Belongs to the SAICAR synthetase family. | 0.780 |
HDEF_0787 | purD | HDEF_0787 | HDEF_2036 | Colicin V production protein; COG1286. | Phosphoribosylglycinamide synthetase (GAR synthetase); COG0151; Belongs to the GARS family. | 0.542 |
HDEF_0787 | purE | HDEF_0787 | HDEF_0294 | Colicin V production protein; COG1286. | N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.724 |
HDEF_0787 | purF | HDEF_0787 | HDEF_0788 | Colicin V production protein; COG1286. | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.955 |
HDEF_0787 | purH | HDEF_0787 | HDEF_2035 | Colicin V production protein; COG1286. | Bifunctional: IMP cyclohydrolase (N-terminal); COG0138. | 0.545 |
HDEF_0787 | purK | HDEF_0787 | HDEF_0295 | Colicin V production protein; COG1286. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.542 |
HDEF_0787 | purL | HDEF_0787 | HDEF_0875 | Colicin V production protein; COG1286. | Phosphoribosylformyl-glycineamide synthetase (FGAM synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.980 |
HDEF_0787 | purM | HDEF_0787 | HDEF_0691 | Colicin V production protein; COG1286. | Phosphoribosylaminoimidazole synthetase (AIR synthetase); COG0150. | 0.759 |
HDEF_0787 | purN | HDEF_0787 | HDEF_0692 | Colicin V production protein; COG1286. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.564 |
purB | purC | HDEF_0557 | HDEF_1837 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); COG0152; Belongs to the SAICAR synthetase family. | 0.995 |
purB | purD | HDEF_0557 | HDEF_2036 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide synthetase (GAR synthetase); COG0151; Belongs to the GARS family. | 0.954 |
purB | purE | HDEF_0557 | HDEF_0294 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.935 |
purB | purF | HDEF_0557 | HDEF_0788 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
purB | purH | HDEF_0557 | HDEF_2035 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional: IMP cyclohydrolase (N-terminal); COG0138. | 0.994 |
purB | purK | HDEF_0557 | HDEF_0295 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.937 |
purB | purL | HDEF_0557 | HDEF_0875 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformyl-glycineamide synthetase (FGAM synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
purB | purM | HDEF_0557 | HDEF_0691 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole synthetase (AIR synthetase); COG0150. | 0.878 |
purB | purN | HDEF_0557 | HDEF_0692 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.904 |
purC | HDEF_0787 | HDEF_1837 | HDEF_0787 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); COG0152; Belongs to the SAICAR synthetase family. | Colicin V production protein; COG1286. | 0.780 |
purC | purB | HDEF_1837 | HDEF_0557 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase); COG0152; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.995 |