node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HDEF_2328 | lolB | HDEF_2328 | HDEF_2119 | Cytochrome c assembly protein; COG4137. | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.615 |
HDEF_2328 | rlpB | HDEF_2328 | HDEF_2039 | Cytochrome c assembly protein; COG4137. | Minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.425 |
HDEF_2328 | zipA | HDEF_2328 | HDEF_0768 | Cytochrome c assembly protein; COG4137. | Cell division protein involved in FtsK recruitment to Z ring; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.551 |
cspC | lepB | HDEF_0826 | HDEF_0531 | Cold shock protein, transcription antiterminator, affects expression of rpoS and uspA; COG1278. | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | 0.578 |
cspC | lolB | HDEF_0826 | HDEF_2119 | Cold shock protein, transcription antiterminator, affects expression of rpoS and uspA; COG1278. | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.580 |
cspC | minE | HDEF_0826 | HDEF_0022 | Cold shock protein, transcription antiterminator, affects expression of rpoS and uspA; COG1278. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.765 |
ispE | lolB | HDEF_2120 | HDEF_2119 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.823 |
lepB | cspC | HDEF_0531 | HDEF_0826 | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | Cold shock protein, transcription antiterminator, affects expression of rpoS and uspA; COG1278. | 0.578 |
lepB | lolB | HDEF_0531 | HDEF_2119 | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.784 |
lepB | lspA | HDEF_0531 | HDEF_0832 | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | Prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.489 |
lepB | minE | HDEF_0531 | HDEF_0022 | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.956 |
lepB | ompA | HDEF_0531 | HDEF_0224 | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | Outer membrane protein 3a (II*;G;d); COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.796 |
lolA | lolB | HDEF_0798 | HDEF_2119 | Periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.736 |
lolA | ompA | HDEF_0798 | HDEF_0224 | Periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Outer membrane protein 3a (II*;G;d); COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.525 |
lolA | rlpB | HDEF_0798 | HDEF_2039 | Periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.524 |
lolB | HDEF_2328 | HDEF_2119 | HDEF_2328 | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Cytochrome c assembly protein; COG4137. | 0.615 |
lolB | cspC | HDEF_2119 | HDEF_0826 | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Cold shock protein, transcription antiterminator, affects expression of rpoS and uspA; COG1278. | 0.580 |
lolB | ispE | HDEF_2119 | HDEF_2120 | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.823 |
lolB | lepB | HDEF_2119 | HDEF_0531 | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Leader peptidase (signal peptidase I), serine protease; COG0681; Belongs to the peptidase S26 family. | 0.784 |
lolB | lolA | HDEF_2119 | HDEF_0798 | Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.736 |