node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Vdis_0575 | Vdis_0579 | Vdis_0575 | Vdis_0579 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | 0.999 |
Vdis_0575 | Vdis_0581 | Vdis_0575 | Vdis_0581 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918:IPR016188:IPR000728; KEGG: cma:Cmaq_0665 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: A8MCJ9 Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. | 0.999 |
Vdis_0575 | Vdis_2131 | Vdis_0575 | Vdis_2131 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR013539:IPR020557:IPR003031:IPR 008948; KEGG: cma:Cmaq_0020 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; SPTR: A8M9J3 Adenylosuccinate lyase domain protein; PFAM: Lyase; Adenylosuccinate lyase C-terminal. | 0.953 |
Vdis_0575 | purC | Vdis_0575 | Vdis_0580 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR018236:IPR001636:IPR013816; KEGG: cma:Cmaq_0664 phosphoribosylaminoimidazolesuccinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: A8MCJ8 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.999 |
Vdis_0575 | purE | Vdis_0575 | Vdis_0585 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
Vdis_0575 | purF | Vdis_0575 | Vdis_0583 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.941 |
Vdis_0575 | purK | Vdis_0575 | Vdis_0586 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.986 |
Vdis_0575 | purL | Vdis_0575 | Vdis_0584 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.999 |
Vdis_0575 | purQ | Vdis_0575 | Vdis_0576 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.999 |
Vdis_0575 | purT | Vdis_0575 | Vdis_0577 | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.991 |
Vdis_0579 | Vdis_0575 | Vdis_0579 | Vdis_0575 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylformylglycinamidine synthetase PurS; InterPro IPR003850; KEGG: cma:Cmaq_0662 hypothetical protein; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: A8MCJ6 Putative uncharacterized protein; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein. | 0.999 |
Vdis_0579 | Vdis_0581 | Vdis_0579 | Vdis_0581 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918:IPR016188:IPR000728; KEGG: cma:Cmaq_0665 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: A8MCJ9 Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. | 0.999 |
Vdis_0579 | Vdis_2131 | Vdis_0579 | Vdis_2131 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR013539:IPR020557:IPR003031:IPR 008948; KEGG: cma:Cmaq_0020 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; SPTR: A8M9J3 Adenylosuccinate lyase domain protein; PFAM: Lyase; Adenylosuccinate lyase C-terminal. | 0.999 |
Vdis_0579 | purC | Vdis_0579 | Vdis_0580 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR018236:IPR001636:IPR013816; KEGG: cma:Cmaq_0664 phosphoribosylaminoimidazolesuccinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: A8MCJ8 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.999 |
Vdis_0579 | purE | Vdis_0579 | Vdis_0585 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
Vdis_0579 | purF | Vdis_0579 | Vdis_0583 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.997 |
Vdis_0579 | purK | Vdis_0579 | Vdis_0586 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.999 |
Vdis_0579 | purL | Vdis_0579 | Vdis_0584 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.999 |
Vdis_0579 | purQ | Vdis_0579 | Vdis_0576 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.999 |
Vdis_0579 | purT | Vdis_0579 | Vdis_0577 | COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR016185:IPR011054:IPR020562:IPR020561:IPR 020560:IPR000115:IPR011761:IPR013817:IPR013816; KEGG: cma:Cmaq_0663 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: A8MCJ7 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synt [...] | ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.980 |