STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Vdis_1499FAD dependent oxidoreductase; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR000447; KEGG: cma:Cmaq_1799 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: A8MAZ1 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. (429 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 0.984
Vdis_1498
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129:IPR017946; KEGG: cma:Cmaq_0606 glycerophosphodiester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: A8MCE1 Glycerophosphodiester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
 
 
 0.940
Vdis_1403
FAD dependent oxidoreductase; COGs: COG0579 dehydrogenase; InterPro IPR006076; KEGG: tsi:TSIB_0771 predicted dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: C6A2I7 Predicted dehydrogenase; PFAM: FAD dependent oxidoreductase.
 
  
 0.935
Vdis_2125
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
 
  
 0.934
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
 
  
 0.933
Vdis_0270
FAD dependent oxidoreductase; COGs: COG0579 dehydrogenase; InterPro IPR006076:IPR007419; KEGG: tpe:Tpen_1375 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: A1RZZ2 FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase.
 
  
0.926
Vdis_0272
Carbohydrate kinase, FGGY; COGs: COG0554 Glycerol kinase; InterPro IPR018484:IPR018485; KEGG: tpe:Tpen_1373 carbohydrate kinase, FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: A1RZZ0 Carbohydrate kinase, FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain.
 
 0.899
Vdis_1500
Carbon monoxide dehydrogenase subunit G; COGs: COG3427 conserved hypothetical protein; InterPro IPR010419; KEGG: cma:Cmaq_1798 carbon monoxide dehydrogenase subunit G; PFAM: carbon monoxide dehydrogenase subunit G; SPTR: A8MAZ0 Carbon monoxide dehydrogenase subunit G; PFAM: Carbon monoxide dehydrogenase subunit G (CoxG).
       0.835
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 
 0.685
Vdis_1497
General substrate transporter; InterPro IPR005828:IPR016196:IPR003663; KEGG: cma:Cmaq_0712 general substrate transporter; PFAM: General substrate transporter; SPTR: A8MCP2 General substrate transporter; PFAM: Sugar (and other) transporter.
 
     0.681
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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