STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_2313COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821:IPR006311:IPR017909; KEGG: pcl:Pcal_1575 nickel-dependent hydrogenase small subunit; SPTR: A3MWH6 Nickel-iron dehydrogenase small subunit, N-terminal domain protein; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); Tat (twin-arginine translocation) pathway signal sequence. (449 aa)    
Predicted Functional Partners:
Vdis_2308
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR018194:IPR001501; KEGG: pcl:Pcal_1578 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: A3MWH9 Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.999
Vdis_2318
(NiFe) hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterProIPR004421:IPR017968:IPR001792:IPR006070:IPR 017945:IPR011125; KEGG: pis:Pisl_0207 (NiFe) hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; SPTR: A1RR07 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; [NiFe] hydrogenase maturation [...]
 
 
 
 0.924
Vdis_2098
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR006067; KEGG: pas:Pars_1213 hydrogensulfite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: A4WK64 Hydrogensulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
  
  
 0.920
Vdis_2099
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR011808:IPR005117:IPR006067:IPR017896; KEGG: pai:PAE2597 sulfite reductase beta subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Hydrogensulfite reductase; SPTR: Q8ZUV0 Sulfite reductase beta subunit; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductas [...]
  
  
 0.919
Vdis_2316
Hydrogenase formation HypD protein; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: pis:Pisl_0205 hydrogenase formation HypD protein; PFAM: hydrogenase formation HypD protein; SPTR: A1RR05 Hydrogenase formation HypD protein; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.918
Vdis_2307
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: pcl:Pcal_1579 hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; SPTR: A3MWI0 Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
  
  
 0.846
Vdis_2319
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854:IPR016188:IPR010918:IPR000728; KEGG: pis:Pisl_0203 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: A1RR03 Hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
   
 0.822
Vdis_2312
KEGG: pis:Pisl_0201 hypothetical protein; SPTR: A1RR01 Putative uncharacterized protein.
     
 0.800
Vdis_2314
Hypothetical protein; InterPro IPR016174; KEGG: dps:DP1985 deca-heme C-type cytochrome; SPTR: Q6ALR1 Similar to deca-heme c-type cytochrome; PFAM: Cytochrome b(N-terminal)/b6/petB.
     
 0.789
Vdis_2311
Hypothetical protein; KEGG: low complexity orf; SPTR: Q59QH9 Putative uncharacterized protein.
       0.773
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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