STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADG91825.1Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001756:IPR006121:IPR018303:IPR 017969:IPR000150:IPR008250:IPR005834:IPR006403:IPR006416; KEGG: ccv:CCV52592_0531 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: C6RIF9 Copper-translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: [...] (726 aa)    
Predicted Functional Partners:
ADG91824.1
InterPro IPR006121; KEGG: tdn:Suden_0772 heavy metal transport/detoxification protein; SPTR: Q30SI0 Heavy metal transport/detoxification protein.
  
 
 0.969
ADG91826.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867; KEGG: abu:Abu_0060 two-component response regulator; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: A8EQX1 Two-component response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.671
ADG91827.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: abu:Abu_0061 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: A8EQX2 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
    0.600
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
       0.557
ADG91831.1
Heavy metal efflux pump, CzcA family; COGs: COG3696 Putative silver efflux pump; InterPro IPR001036:IPR004763; KEGG: abu:Abu_0065 heavy metal efflux pump; PFAM: acriflavin resistance protein; SPTR: A8EQX6 Heavy metal efflux pump; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.505
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.441
ADG91814.1
AAA ATPase central domain protein; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: abu:Abu_0049 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: A8EQW0 ATPase, AAA family protein; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus.
 
     0.439
ADG91830.1
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: abu:Abu_0064 cation efflux system, membrane fusion protein; SPTR: A8EQX5 Cation efflux system, membrane fusion protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit.
  
  
 0.437
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
     
 0.430
ADG91829.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: abu:Abu_0063 hypothetical protein; PFAM: outer membrane efflux protein; SPTR: A8EQX4 Putative uncharacterized protein; PFAM: Outer membrane efflux protein.
  
    0.423
Your Current Organism:
Arcobacter nitrofigilis
NCBI taxonomy Id: 572480
Other names: A. nitrofigilis DSM 7299, Arcobacter nitrofigilis DSM 7299, Arcobacter nitrofigilis str. DSM 7299, Arcobacter nitrofigilis strain DSM 7299
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