STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADE56865.1TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: gur:Gura_2507 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein. (1144 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.999
ADE56151.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.993
ADE57176.1
KEGG: pca:Pcar_1692 DNA polymerase III, gamma/tau subunits.
   
 0.993
ADE57689.1
KEGG: dma:DMR_30070 hypothetical protein.
  
 0.991
ADE56824.1
PFAM: DNA polymerase III delta.
  
 
 0.942
ADE57538.1
KEGG: mxa:MXAN_1071 single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
   
 
 0.925
ADE56866.1
KEGG: dps:DP3116 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
  
 0.912
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
     
 0.790
ADE56867.1
PFAM: NUDIX hydrolase; KEGG: pin:Ping_0696 nucleotide phosphate derivative pyrophosphohydrolases, MutT/NUDIX family protein.
     
 0.787
ADE56869.1
PFAM: alanine racemase domain protein; KEGG: mlo:mlr5700 hypothetical protein.
       0.756
Your Current Organism:
Aminobacterium colombiense
NCBI taxonomy Id: 572547
Other names: A. colombiense DSM 12261, Aminobacterium colombiense DSM 12261, Aminobacterium colombiense str. DSM 12261, Aminobacterium colombiense strain DSM 12261
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