STRINGSTRING
crl protein (Klebsiella pneumoniae) - STRING interaction network
"crl" - Sigma factor-binding protein Crl in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlSigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (132 aa)    
Predicted Functional Partners:
frsA
Uncharacterized protein; Forms a 1-1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; Derived by automated computational analysis using gene prediction method- Protein Homology (414 aa)
 
          0.913
JG24_30355
Derived by automated computational analysis using gene prediction method- Protein Homology (128 aa)
   
          0.729
JG24_28115
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (68 aa)
   
          0.693
JG24_14360
Derived by automated computational analysis using gene prediction method- Protein Homology (374 aa)
   
          0.666
JG24_03655
Outer membrane pore protein E; Derived by automated computational analysis using gene prediction method- Protein Homology (350 aa)
   
          0.661
JG24_17635
Outer membrane protein C; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Gram-negative porin family (370 aa)
   
          0.654
JG24_16275
Outer membrane protein N; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Gram-negative porin family (381 aa)
   
          0.639
cyaA
Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3’-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the adenylyl cyclase class-1 family (850 aa)
   
          0.629
JG24_18580
Derived by automated computational analysis using gene prediction method- Protein Homology (344 aa)
   
          0.624
JG24_10250
Outer membrane protein N; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method- Protein Homology (374 aa)
   
          0.618
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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