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JG24_03835 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_03835" - Delta-aminolevulinic acid dehydratase in Klebsiella pneumoniae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
JG24_03835Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family (324 aa)    
Predicted Functional Partners:
hemC
Transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (313 aa)
 
  0.994
JG24_30310
Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (426 aa)
 
 
  0.991
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (418 aa)
 
   
  0.924
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (457 aa)
 
 
  0.860
JG24_20125
Derived by automated computational analysis using gene prediction method- Protein Homology (471 aa)
 
 
  0.860
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)
 
 
  0.858
hemD
Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (246 aa)
   
 
  0.804
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (460 aa)
 
 
 
  0.797
ubiE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (251 aa)
 
   
  0.675
JG24_18420
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (299 aa)
   
   
  0.671
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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