STRINGSTRING
iraP protein (Klebsiella pneumoniae) - STRING interaction network
"iraP" - Anti-adapter protein IraP in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iraPAnti-adapter protein IraP; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (86 aa)    
Predicted Functional Partners:
mzrA
Modulator protein MzrA; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (127 aa)
   
     
  0.767
JG24_23735
Derived by automated computational analysis using gene prediction method- Protein Homology (177 aa)
   
          0.758
JG24_14875
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (94 aa)
   
          0.750
JG24_09770
Derived by automated computational analysis using gene prediction method- Protein Homology (72 aa)
   
          0.747
JG24_24540
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (96 aa)
   
          0.741
JG24_06540
Putative inner membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (136 aa)
   
          0.740
JG24_26525
Putative lipoprotein; Derived by automated computational analysis using gene prediction method- Protein Homology (67 aa)
   
          0.728
JG24_05160
Derived by automated computational analysis using gene prediction method- Protein Homology (82 aa)
   
          0.727
JG24_03865
Putative inner membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (67 aa)
   
          0.725
JG24_18215
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (115 aa)
   
          0.722
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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