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ribH protein (Klebsiella pneumoniae) - STRING interaction network
"ribH" - 6,7-dimethyl-8-ribityllumazine synthase in Klebsiella pneumoniae
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family (156 aa)    
Predicted Functional Partners:
ribD
5-amino-6-(5-phosphoribosylamino)uracil reductase; Riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; Derived by automated computational analysis using gene prediction method- Protein Homology (367 aa)
 
 
  0.999
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; functions during riboflavin biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (217 aa)
 
  0.999
JG24_13740
Riboflavin synthase eubacterial/eukaryotic; Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; Derived by automated computational analysis using gene prediction method- Protein Homology (211 aa)
 
  0.995
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (200 aa)
 
   
  0.991
nusB
Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons (139 aa)
 
   
  0.990
JG24_06850
Protein ybjI; Derived by automated computational analysis using gene prediction method- Protein Homology (270 aa)
       
    0.904
JG24_26545
YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; Derived by automated computational analysis using gene prediction method- Protein Homology (238 aa)
       
    0.901
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (609 aa)
   
  0.828
JG24_23345
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA (431 aa)
   
   
  0.766
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (149 aa)
 
   
  0.761
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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